Bad Pharma: How Medicine is Broken, And How We Can Fix It et plus d'un million d'autres livres sont disponibles pour le Kindle d'Amazon. En savoir plus
EUR 7,80
  • Tous les prix incluent la TVA.
Il ne reste plus que 2 exemplaire(s) en stock.
Expédié et vendu par Amazon.
Emballage cadeau disponible.
Quantité :1
Bad pharma a été ajouté à votre Panier
Amazon rachète votre
article EUR 0,77 en chèque-cadeau.
Vous l'avez déjà ?
Repliez vers l'arrière Repliez vers l'avant
Ecoutez Lecture en cours... Interrompu   Vous écoutez un extrait de l'édition audio Audible
En savoir plus
Voir les 2 images

Bad pharma (Anglais) Broché – 2013


Voir les 8 formats et éditions Masquer les autres formats et éditions
Prix Amazon Neuf à partir de Occasion à partir de
Format Kindle
"Veuillez réessayer"
Broché
"Veuillez réessayer"
EUR 7,80
EUR 7,08 EUR 9,27
--Ce texte fait référence à une édition épuisée ou non disponible de ce titre.

Offres spéciales et liens associés


Produits fréquemment achetés ensemble

Bad pharma + Bad Science + Irrationality: The Enemy Within
Prix pour les trois: EUR 31,22

Acheter les articles sélectionnés ensemble

Descriptions du produit

Revue de presse

Praise for Bad Science
"One of the best books I've ever read. It completely changed the way I saw the world. And I actually mean it." -- Tim Harford, author of The Undercover Economist

"This is a much-needed book. Ben Goldacre shows us -- with hysterical wit -- how to separate the scam artists from real science. In a world of misinformation, this is a rare gem." -- Timothy Ferriss, author of The 4-Hour Workweek --Ce texte fait référence à une édition épuisée ou non disponible de ce titre.

Présentation de l'éditeur

We all feel uncomfortable about the role of profit in healthcare, we all have a vague notion that the global $600bn pharmaceutical industry is somehow evil and untrustworthy, but that sense rarely goes beyond a flaky, undifferentiated new age worldview. Bad Pharma puts real flesh on those bones, revealing the rigged evidence used by drug companies. Bad information means bad treatment decisions, which means patients suffer and die: there is no climactic moment of villainy, but drugs are used which are overpriced, less effective, and have more side effects. There are five cheap, easy things we can do to fix the problem. Bad Pharma takes a big dirty secret out into the open, and will provide a single focus for concerns people have both inside and outside medicine.

--Ce texte fait référence à une édition épuisée ou non disponible de ce titre.


Vendez cet article - Prix de rachat jusqu'à EUR 0,77
Vendez Bad pharma contre un chèque-cadeau d'une valeur pouvant aller jusqu'à EUR 0,77, que vous pourrez ensuite utiliser sur tout le site Amazon.fr. Les valeurs de rachat peuvent varier (voir les critères d'éligibilité des produits). En savoir plus sur notre programme de reprise Amazon Rachète.

Détails sur le produit

  • Broché: 462 pages
  • Editeur : 4th (2013)
  • Collection : 4 th
  • Langue : Anglais
  • ISBN-10: 000749808X
  • ISBN-13: 978-0007498086
  • Dimensions du produit: 16,8 x 3,6 x 19,7 cm
  • Moyenne des commentaires client : 4.7 étoiles sur 5  Voir tous les commentaires (3 commentaires client)
  • Classement des meilleures ventes d'Amazon: 22.570 en Livres anglais et étrangers (Voir les 100 premiers en Livres anglais et étrangers)
  •  Souhaitez-vous compléter ou améliorer les informations sur ce produit ? Ou faire modifier les images?


En savoir plus sur l'auteur

Découvrez des livres, informez-vous sur les écrivains, lisez des blogs d'auteurs et bien plus encore.

Dans ce livre

(En savoir plus)
Parcourir les pages échantillon
Couverture | Copyright | Table des matières | Extrait | Index
Rechercher dans ce livre:

Quels sont les autres articles que les clients achètent après avoir regardé cet article?

Commentaires en ligne

4.7 étoiles sur 5
5 étoiles
2
4 étoiles
1
3 étoiles
0
2 étoiles
0
1 étoiles
0
Voir les 3 commentaires client
Partagez votre opinion avec les autres clients

Commentaires client les plus utiles

2 internautes sur 2 ont trouvé ce commentaire utile  Par adrideo le 17 juin 2013
Format: Format Kindle Achat vérifié
Même si l'on sait que l'industrie pharmaceutique est un monde de business uniquement intéressé par l'argent, la lecture de ce livre est extrêmement intéressante. Les détails relatifs aux tests pharmaceutiques et à la publication des résultats sont effrayants. L'auteur documente beaucoup ces propos et est passionné. Je recommande vivement ce livre.
Remarque sur ce commentaire Avez-vous trouvé ce commentaire utile ? Oui Non Commentaire en cours d'envoi...
Merci pour votre commentaire. Si ce commentaire est inapproprié, dites-le nous.
Désolé, nous n'avons pas réussi à enregistrer votre vote. Veuillez réessayer
Format: Broché Achat vérifié
Ce livre permet d'avoir une idée juste du fonctionnement de l'industrie pharmaceutique au sens large du terme. En effet, il est question ici de la totalité de la chaine du médicament : du chimiste au consommateur, en passant par les instances de régulations.

C'est un cadeau que nous fait ici Ben Goldacre en permettant avec un livre simple, bien écrit et clair de connaitre les raisons des scandales qui entourent cette industrie. Il réussit l'exploit d'éviter les faiblesses habituelles du genre, à savoir un discourt moralisateur où l'ont porte un acteur en pâture sans voire la totalité du problème.

Si vous êtes un minimum intéressé par cette problématique, et vous l'êtes assurément en lisant ceci, ce livre est à lire absolument.

Le seul petit défaut, il n'est pas encore traduit en français mais il vaut très largement l'effort.
Remarque sur ce commentaire Avez-vous trouvé ce commentaire utile ? Oui Non Commentaire en cours d'envoi...
Merci pour votre commentaire. Si ce commentaire est inapproprié, dites-le nous.
Désolé, nous n'avons pas réussi à enregistrer votre vote. Veuillez réessayer
2 internautes sur 3 ont trouvé ce commentaire utile  Par Francisca le 14 mars 2013
Format: Broché
I think that we all know too little about what goes on the world of the pharmaceutical industry and if we were better informed maybe we would look at our doctor and what he prescribes us with very different eyes! We still want to believe that the world is, if not perfect quite good and that no one would hurt us on purpose and surely not only in order to make money but well.... The truth is that we live in a capitalist society where profits go above everything else and yes... people do hurt us, if not on purpose at least knowingly, others hurt us because they don't really care about anything else but they own financial well being, etc. We are now responsible for our own health and think otherwise is put ourselves and our families in danger! Either we want to get informed and try to protect ourselves as well as we possibly can, either we don't and then we are responsible for what happens to us. We can't wait for strangers to take the responsibility! The era of the nice village doctor who really cared if gone maybe forever! Now you have people who will make a lot of money because of the fact that you are ill, a lot more than if you were healthy and trying to keep you healthy is not an option for them. Sometimes making you more ill it is! Ben Goldacre is a doctor and therefore is somehow biased on some subjects but he is not afraid to say what he thinks and to dig till he gets a lot of dirt out. A dangerous business if you ask me.... But well, he is not afraid to do it!

As I said I don't agree with everything he says. His distrust of homeopathy is shared by many within the allopathic establishment and I am sure that there are some quacks around in the natural medicine, of course there are, but there are a lot of good therapies as well!
Lire la suite ›
Remarque sur ce commentaire Avez-vous trouvé ce commentaire utile ? Oui Non Commentaire en cours d'envoi...
Merci pour votre commentaire. Si ce commentaire est inapproprié, dites-le nous.
Désolé, nous n'avons pas réussi à enregistrer votre vote. Veuillez réessayer

Commentaires client les plus utiles sur Amazon.com (beta)

Amazon.com: 158 commentaires
99 internautes sur 103 ont trouvé ce commentaire utile 
Another killer blow from the pen of Dr. Goldacre 27 septembre 2012
Par Guy Chapman - Publié sur Amazon.com
Format: Format Kindle
It is a common claim among alt med cranks that skeptics are only critical of alternative medicine. This is not and has never been true - most of Bad Science is about "Big Pharma" and its shenanigans, but this latest book by Ben Goldacre goes a lot further.

In "Bad Pharma" you will read about the ways in which vested interests bamboozle us and our doctors, whether by accident or design. You will find out why the benefits of most medicines are overstated, and why the systematic review is incredibly important. You will become, in short order, very angry indeed, and then you will be told what you can do about that anger - whether you are a patient or a doctor.

Goldacre's style is engaging and informal, and he is a practising doctor. The books include anecdotes about how he himself has unknowingly prescribed drugs which are not just ineffective, but worse than doing nothing - despite having read the research evidence with a particularly critical eye. All the data and references are there if you need them but they don't derail the narrative, so the book functions both as a reference and as an eminently readable story.

This is my pick for best book of the year so far, and one of the most important books most of us will have read. This is about your health. Get informed, get angry and get active!
47 internautes sur 48 ont trouvé ce commentaire utile 
The Upton Sinclair of Pharma.... 9 février 2013
Par OSS architect - Publié sur Amazon.com
Format: Relié
Dr Goldacre is an Epidemiologist, as am I. Or was. I changed fields because I saw examples, first hand, of what Dr Goldacre exposes in his book. Proper clinical trials are very difficult and expensive to do. You get obvious bad data in the raw observations, sample sizes are less than you want. Your power calculation on the sample size you have and the results you got suggest your P-value is bogus. You have to make judgements in some very grey areas. Every day.

You work with research MDs that won't have a career if they don't get results. As an Epidemiologist you work part time on numerous small grants that don't add up to an adequate salary, so many of us do (did) statistical work for drug company trials. You don't get recommended for further consulting work if you are "overly rigorous", shall we say.

In the late 70's new FDA requirements caused everyone to step up their game, but at increasing expense to doing trials. To contains costs, 30 years later, trials are now outsourced to about a half dozen separate specialist companies each doing one part of the study. A Clinical program management company, a data staging company, various companies that do the raw analysis (e.g. reading of CAT, MRI data), a company that prepares the results according to FDA submission requirements. All of them competing for the next contract, and competing on cost.

You can see where this is going....

I never witnessed any truly unethical behavior. There is no evil here. Personally, I chose to go into the software industry to avoid having to make daily ethical decisions. Dr. Goldacre wrote the book that many Epidemiologists could write. Hats off to him for actually doing it.

This ex-Epidemiologist only takes generic drugs, because the only good clinical trial is done on the general public, and after it comes off-patent, it's been around long enough to know it's efficacy and side effects.
46 internautes sur 47 ont trouvé ce commentaire utile 
A tough reality check on drug companies and legislation 15 octobre 2012
Par Martin Orsted - Publié sur Amazon.com
Format: Format Kindle Achat vérifié
Bad Pharma highlights serious issues with the way the pharmaceutical industry works today. In the book Ben highlights the problems with the industry from several angles, how the tests can be tweaked, how negative tests are not published, how you can make a neutral test appear positive by sub-dividing the goals and then emphasize the fluke positive one. He also shows how the medical journals are part of the problem and the issue with ghost written articles. He shows the problems with the regulatory side as well, for example the European Medicines Agency, their lack of transparency, and how they have effectively blocked access to critical data for researchers. All through the book Ben makes use of well documented examples, and all the issues highlighted are well documented and exemplified.

The book is written in an easy to access language, and so it reads well. He does repeat himself a bit, so one more round of editing and cleanup before release would probably have been a good idea. Some readers on amazon.co.uk have criticised this, but I don't see it as an issue.

You don't need to have a degree in medicine or a higher degree in general to understand the issues Ben highlights.

Ben Goldacre runs the Bad Science website (badscience dot net) and has previously written the book Bad Science. Where Bad Science was an attack on quackery and pseudo science, and his website to a large degree has dealt with the same topics, this book is a critical look at the pharmaceutical industry. As such it ought to silence those that have attacked Ben Goldacre for being in the pockets of the Pharmaceutical industry over time.

Ben Goldacre has done society a big favour by writing this book. I definitely recommend reading it if you want to understand more about how US and European health care works and what can be done to improve it in the future.
35 internautes sur 37 ont trouvé ce commentaire utile 
Extensive, well-written and scientific. 11 octobre 2012
Par mrandrewv - Publié sur Amazon.com
Format: Format Kindle Achat vérifié
Ben Goldacre fills a vitally important niche in popular science literature. His books serve as a way of explaining highly technical and complex medical issues in language that is easily understood and with emphasis and focus that makes the seriousness of the issues at hand impossible to ignore.

Goldacre also holds himself to a far higher standard of scientific excellence than the groups he is critiquing, exhaustively referencing, justifying and clarifying his points so that there is no doubt of the accuracy of his claims.

This book sinks a knife into the heart of the nonsense and pseudo-science that is far too often espoused by the pharmaceutical industry and tacitly endorsed by overawed journalists and cowed academics.

If you want to know why the drugs are you taking sometimes don't work and often make you ill then you need to read this book.

And any medical practitioner, academic or researcher who does not read this book should be thoroughly ashamed of themselves.

It is absolutely excellent.
13 internautes sur 13 ont trouvé ce commentaire utile 
An Important Message - 13 février 2013
Par Loyd E. Eskildson - Publié sur Amazon.com
Format: Relié
America's health system is the world's costliest, by far - consuming 18% of GDP, compared to 12% for #2 Switzerland and 8% for serious competitors Taiwan and Japan and only 4% for Singapore. Dr. Ben Goldacre's 'Bad Pharma' helps explain why this is so. In a nutshell, it's because the evidence used to make medical decisions is hopelessly and systematically distorted.

Specifically, drugs are tested mostly by their manufacturers on small numbers of unrepresentative patients, and analyzed using deliberately flawed techniques that exaggerate their benefits. When trials bring results that manufacturers don't like, they're often hid from doctors and patients - thus, we only see distorted pictures of their true effects. And finally, academic papers thought to be objective are often written by those working for the manufacturers, without disclosure. Sometimes the journals are even owned by a drug company.

Some of the stories told by Dr. Goldacre make you question the integrity of those involved, others will make you angry or sad. It's all thanks to perverse incentives. Goldacre justifiably prides himself on using 'systematic reviews' (unbiased surveys of all the evidence) to make his points, using individual studies only to add detail.

Pharmaceutical companies spend twice as much on marketing and advertising as on R&D of new drugs. New drugs must only prove that they are better than nothing, even when highly effective treatments already exist. Data on side effects and effectiveness can be withheld from regulators.

Three researchers in 2010 reviewed all the drug trials (over 500) involving antidepressants, ulcer drugs, and three other major categories. Eighty-five percent of the industry-funded studies were positive, buy only 50% of the government funded trials. Similarly, in 2007 researchers looked at every published trial (192) of cholesterol-lowering statins, and found industry-funded trials 20X more likely to give results favoring the test drug. Cherry-picking of the data explains the differences. Sometimes the result is that hundreds of thousands of patients die, unnecessarily - Avandia, Fen Phen, Vioxx.

Contract Research Organizations are a new phenomenon now providing over half the clinical trials; global revenues of $20 billion in 2010, about one-third of all pharma R&D spending. In 2008 they ran over 9,000 trials, with over 2 million participants in 115 countries. Use of private community doctors in the U.S. for conducting trials has also greatly expanded, with payments near $1 million for the most enterprising. Quintiles, the largest CRO company offers to help drug companies 'better identify, promote, and prove the value of a particular drug to key stakeholders.' Some CRO contracts share the risk of a poor outcome with the drug companies, further increasing the likelihood of of slanted results beyond simply the desire to retain business. Running a trial in the U.S. costs $30,000/patient (per a GSK executive), $3,000 in Romania. Thus, lots of outsourcing to poorer countries where regulatory oversight is poorer and corruption more prevalent. Genetic differences in drug reactions present another problem.

Lobbyists help get their way via sponsoring socializing events, hiring leading experts as consultants or advisers, giving out research grands, and hiring former regulators. Similarly with those sitting on agency advisory boards. It is becoming increasingly difficult to find members of advisory boards who are not compromised in some way. Often drugs are approved despite showing no benefit to real-world outcomes such as heart attacks or death - eg. statins vs. cholesterol levels and heart attacks, anti-arrhythmic drugs vs. death rates (doxazosin - CAST study). Detecting side effects can require years.

Drug marketers sometimes use biased surveys. Example - Eli Lilly posed ten Internet questions to detect potential depression; answering 'No' to all ten brought a 'You may be at risk for major depression' response. Drug-company sponsored CME programs are another problem.

Drug firms have been fined up to $3 billion (GSK), but Goldacre says this is minor compared to the revenues involved.
Bottom-Line: Readers will be well served by 'Bad Pharma' and the lessons it offers.
Ces commentaires ont-ils été utiles ? Dites-le-nous


Commentaires

Souhaitez-vous compléter ou améliorer les informations sur ce produit ? Ou faire modifier les images?