This review pertains to the Kindle Edition.
First, had Amazon or the publisher indicated that this was included as a chapter in Flanagan's recently published JavaScript: The Definitive Guide: Activate Your Web Pages, I wouldn't have bought it--but I downloaded both at the same time and didn't find out until a couple days later. That's why I gave the book a 4-start rating rather than 5. If you are a DTB user then it makes sense to have both because you're unlikely to want to carry around an 1100 page volume as a quick reference, but for a Kindle user with full text search available buying this is a waste of money if you are going to buy the other. That, in fact is my recommendation: buy the larger book and park it on your development workstation.
That said, this is a fine piece of work. Like many developers, I started using a JavaScript library for a particular project and settled on jQuery because it provided the features I needed at the time. I came to understand its value and used in increasingly, but always with a familiarity constrained by the requirements of my initial use. My skills grew as I used it, but slowly.
So, I really welcomed and valued the first 2/3 (or so) of Flanagan's book (or chapter), which is a narrative description of the library's features, with examples and detailed explanations of what's going on behind the scenes. Writing that sort of narrative about a programming language is hard, and Flanagan's only peer for that, in my opinion, is Friedl of Mastering Regular Expressions (also an O'Reilly book), and he succeeded here well enough that a person can actually read the whole thing with considerable understanding, thereby gaining a better overview of the library than can be had by searching out features when we bump up against something we don't know how to do. The last 1/3 of the book is a reference section: concise, simple, and well-organized, just what you need when you forget a particular syntax.
The book was carefully adapted to electronic viewing. Code is displayed in a fixed space font to differentiate it from the surrounding text, but the font has the same height and color as the text and so is easy to read. Sidebars are presented with a slightly smaller, but still easily readable font, as a distinct block of text embedded with the main text. This, and the larger work from which it was extracted, are the best examples of technical books adapted to e-readers I have seen, so O'Reilly deserves considerable credit for their success in this format.
The book was written for jQuery version 1.4 and the current version is 1.6.1 (as of today), and quite a bit has been added to jQuery. I knew that before I bought the book and decided the reference retained enough value to be worthwhile even though the version had been superseded. You should bear that in mind, though.