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Niacin: The Real Story (English Edition) [Format Kindle]

Abram Hoffer , Andrew W. Saul , Harold D. Foster

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Niacin (vitamin B3) is a small molecule-made of only 14 atoms-smaller even than the simplest sugar.But this one molecule has profound effects on health: it plays a role in more than 500 reactions in the body. Many illnesses are caused by too little niacin, and many illnesses can be cured with mega doses of niacin. The authors of "Niacin: The Real Story" are advocates of orthomolecular (nutrition-based) medicine, support an approach to wellness that involves substances that naturally occur in the human body, such as niacin. This book makes the case for the widespread use of niacin for the prevention and treatment of health problems. "Niacin: The Real Story" is for people who want to learn more about niacin and its wonderful healing properties.

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  • Format : Format Kindle
  • Taille du fichier : 901 KB
  • Nombre de pages de l'édition imprimée : 240 pages
  • Editeur : Basic Health Publications, Inc.; Édition : 1st (1 février 2012)
  • Vendu par : Amazon Media EU S.à r.l.
  • Langue : Anglais
  • ASIN: B0074NDA1W
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Amazon.com: 4.7 étoiles sur 5  130 commentaires
142 internautes sur 147 ont trouvé ce commentaire utile 
5.0 étoiles sur 5 Niacin, a B Vitamin, Can Help to Restore and Maintain Health 15 mars 2012
Par Robert Sealey - Publié sur Amazon.com
Niacin: The Real Story
By A Hoffer, PhD, MD, A Saul, PhD and H Foster, PhD, 2012, Basic Health, CA

Abram Hoffer, Andrew Saul and Harold Foster wrote Niacin: The Real Story to let the public know that niacin (vitamin B3) has a broad spectrum of healing properties. Decades of research, references and recoveries taught Dr. Hoffer that niacin therapy can help patients who have deficiencies or metabolic disorders which can cause or contribute to mental, cardiovascular, arthritic and other illnesses.

Abram Hoffer was a PhD-MD student in the 1930s and 1940s, when vitamins had only just been discovered. In those years, as soon as doctors learned that nutritional supplements could help, physicians began to prescribe vitamins. Abram Hoffer read their research papers and progress reports. He remembered them.

Meanwhile, year after year, pharmaceutical manufacturers synthesized hundreds of compounds, researched their efficacy and promoted their use in medicine. Prescription drug-making became the most profitable industry in history. Marketing campaigns taught health professionals how and when to prescribe a growing list of pills which affect the human body in many ways, while claiming that the benefits of synthetic chemicals offset their risks and side effects. Drug sales skyrocketed. Of course medications work. Prescription drugs do save lives. However, as the years passed, many health professionals focused on medications and never learned the therapeutic effects of vitamins.

Years of careful reading taught Abram Hoffer that vitamins can help to restore and maintain health, especially when patients have nutritional deficiencies or metabolic disorders. After he became a biochemist, researcher, physician (in 1949) and then a psychiatrist, Dr. Hoffer spent 60 years diagnosing patients and complementing other treatments with vitamins, while researching, developing and writing about orthomolecular medicine as a restorative dimension of care. His original research encouraged him to prescribe health-restoring doses of vitamins. He and his colleague Humphry Osmond performed the first double-blind placebo-controlled scientific experiments in psychiatry and discovered that an optimum dose of niacin helped 75% of patients recover from acute schizophrenia. To educate the public, Abram Hoffer wrote prolifically about vitamins, research and clinical applications. For decades, Dr. Hoffer helped patients recover while mainstream medical professionals dismissed restorative care. Believing that vitamins could not possibly help, they ignored Dr. Hoffer's research and recovery reports. Their closed-minded attitudes withheld vitamin regimens from trusting patients.

Dr. Hoffer often prescribed niacin with other vitamins, minerals and amino acids. He encouraged patients to eat nutritious diets and eliminate trigger foods. He taught many doctors how to complement other treatments with vitamins and modify doses based on each patient's diagnosis, progress and biochemical individuality. Knowing that factors such as biochemical individuality and food allergies and sensitivities can also affect patients' health whether they suffer from deficiencies, disorders or diseases, Abram Hoffer and his orthomolecular colleagues diagnosed carefully and customized vitamin treatment programs. Thousands of patients recovered.

Abram Hoffer died in 2009 at age 91. His legacy left the world more than 35 books and hundreds of articles, reviews and editorials which explain that optimal doses of vitamin B3 (niacin and/or niacinamide), can complement other treatments, including prescription medications. Niacin: The Real Story, his last book, outlines Dr. Hoffer's research, discoveries and clinical recommendations. His references and recovery stories support his concept that vitamin therapy can help to restore health. Adventures in Psychiatry: The Scientific Memoirs of Dr. Abram Hoffer, (2005), details his research, progress and success using vitamins to treat schizophrenia. How to Live with Schizophrenia (1966), written by Hoffer and Osmond for patients and families, still reads fresh and clear today.

Hoffer, Saul and Foster's 2012 book explains what niacin is, how niacin therapy began, how niacin works, why we need more niacin, how to take niacin and why niacin is safe. The only cautionary note concerns niacin's harmless and noticeable but short-lived flush effect. After one week, patients who take niacin every day will flush much less. Abram Hoffer learned about the flush by taking niacin himself, for 55 years! During his 60-year career, Dr. Hoffer prescribed niacin to thousands of patients. His finding? Niacin helped patients recover, feel better and live longer. This book provides research reports, references and recovery stories which justify the clinical use of niacin for mental illness and cardiovascular problems and niacinamide for arthritis. A long chapter outlines how patients with 25 other health problems can also respond to vitamin B3 therapy.

If you or a loved one has a chronic health problem, you can read this book to understand how niacin could help you. Thanks to Abram Hoffer and his
co-authors, Niacin: The Real Story encourages patients, families, caregivers and even health professionals to learn that niacin has a broad spectrum of wonderful healing properties. Depending on each patient's diagnosis and diet, optimum doses of niacin can complement other treatments and help patients recover, safely and effectively.

Review by Robert Sealey, BSc, CA
Author of Finding Care for Depression, Mental Episodes & Brain Disorders
52 internautes sur 52 ont trouvé ce commentaire utile 
5.0 étoiles sur 5 NIACIN'S MIRACULOUS PROPERTIES 29 septembre 2013
Par Amazon Customer - Publié sur Amazon.com
Format:Format Kindle|Achat vérifié
I bought this book more out of curiosity than out of any idea that niacin could make a difference in my life. After reading through the refreshing prose for a while, I was inspired to try some instant niacin myself. The proof, after all, is in the pudding. Was I surprised!

On 600 mg instant niacin a day:

(a) I could suddenly sleep well 7 hours a night (I was taking 300 micrograms melatonin at night which I no longer needed);
(b) Besides going as red as a beet when I took my first two 100 mg tablets, I noticed an immediate boost in mood; yes, niacin often makes me feel high. (I am someone who never drinks or takes drugs.)
(c) My joint pains and muscle pains, which I had for years, went away overnight, almost completely.
(d) I had so much more energy, which remains steady through each day (I was taking carnitine, which I no longer need.)
(e) I had a very unpleasant, painful, protruding pile which had lasted for more than a month, before I began taking niacin. Within 3 days my pile had shrunk, I could hardly feel any lump and the muscle tone in that area felt much better. I haven't had any problems with piles in the 6 months I have been taking niacin, no matter how much I push.
(f) On a gram of slow release niacin, taken in addition to the 600 mg fast niacin a day, my LDL dropped from 5.6 to 3.0 in two weeks. My HDL went from 1.31 to 1.68.

The book is not merely about the many benefits of niacin, but is the story of niacin, of how Dr. Hoffer first came to use it on many of his patients. It is also, in a very real sense, the story of Dr. Hoffer himself, and what a wonderful, inspiring story it is!

According to this book, about 50% of all people in the world can benefit from taking niacin every day. I am clearly one of them. Curiously, the opposite seems to be true for my wife: for one, it aggravated her piles overnight, causing them to flare up painfully, and she experienced no subjective benefits. It is therefore a question of each person must try for himself / herself and closely monitor what they experience. There is a bit of jargon that apparently explains this: under-methylation (me); over-methylation (my wife.)

The only downsides I experienced (I do not see the itching, burning sensation on the skin and the hot flashes which sometimes arise, as such) is that it seemed to aggravate my sinusitis. However, I was able to counteract this effect effectively with curcumin and msm. Further, if taken directly before switching off the light at night, I tended to experienced arythmias (irregular heart beat) while waiting to fall asleep or on waking during the night. So now I take 200 mg about an hour before I switch off the night light, which makes all the difference.

One area the book does not effectively or safely address, which is a bit of a bummer, is clear directions on the use of slow niacin. Reading this book, one can be forgiven for thinking that it would be safe to take 3 grams of slow release niacin a day, instead of 3 grams of fast release niacin, although this book almost exclusively recommends the latter. However, it is in fact quite unsafe to take 3 grams of slow release niacin a day, for every 500 mg of slow release niacin is the equivalent of 1 gram of fast niacin in its effect on the liver. Thus, if you want to substitute slow release niacin for 3 grams of instant niacin, you should take no more than 1.5 grams of slow release niacin a day. This does not mean you will experience exactly the same effect/ benefit if you do. In my case, I find that a gram of slow release niacin (which is the equivalent of two grams of fast niacin) and up to a gram of fast niacin a day produces the best synergy of benefits in me, with each enhancing the other.

This book also recommends inositol hexanicotinate (it says you need to take twice as much as the instant niacin to get the same benefit). I guess the good doctor and Andrew Saul speak from their experience. However, I haven't found this product to be effective at all, and there is mounting evidence that inositol hexanicotinate is not very bio-available.

Besides for these few complaints about the value of this book, I highly recommend it, even if you are not wondering how effective niacin might be for you, and whether you should take it or not. it is written in refreshing, easy to follow, non-jargon prose and if you read it, you will know more about niacin than most medical doctors do.

For lowering cholesterol, 1.5 grams of slow release niacin a day is best, or take a gram of slow release niacin and up to a gram of fast release niacin per day. If you are thinking primarily of your cholesterol, "Cholesterol Control Without Diet! The Niacin Solution" by Dr. William B Parsons Jr. would be more up your alley. However, the latter is not nearly as exciting a read as the current read.

I highly recommend "Niacin - The Real Story".

62 internautes sur 63 ont trouvé ce commentaire utile 
5.0 étoiles sur 5 Niacin the real story 12 mai 2012
Par Gedalya - Publié sur Amazon.com
Format:Broché|Achat vérifié
I found out about this book by Dr. Mercola and I bought it right away. B3 is a water soluble vitamin yet very hard to get from your food intake. It's been well known to increase the HDL while lowering the LDL's and Triglycerides. Some other great benefits for which I started taking Niacin for is Arthritis. It really works great. The flush is hard to take and very intense but it starts to go away after a week compared to the strength it showed in the first week. If you have low HDL,s, Arthritis, Mentally unstable, trigeminal neuralgia this Vitamin is a key ingredient you might be lacking. This book is great and informative.
Also I must recommend The Miracle of MSM the natural solution for pain. Which is also a great book about another great product which works amazingly.
84 internautes sur 88 ont trouvé ce commentaire utile 
5.0 étoiles sur 5 Niacin is a very important nutrient 2 janvier 2012
Par D. R. Schryer - Publié sur Amazon.com
Format:Broché|Achat vérifié
Regrettably most of the orthodox medical establishment pays little attention to the importance of vitamins, minerals, and other essential nutrients except to advise that we should all eat a "good balanced diet" -- which few Americans actually do. Fortunately a few maverick doctors, including Dr. Hoffer and his coauthors, have studied the importance of vitamins, minerals, and other essential nutrients and come to realize that deficiency of one or more of these is the leading cause of many modern ailments. In this book Dr. Hoffer discusses in detail the importance for health of the essential vitamin niacin. This is a book well worth reading -- including by members of the orthodox medical establishment. If everyone got enough of each of various essential nutrients there would be much less need for the pharmaceutical drugs which are widely prescribed to treat the symptoms of modern ailments but whose known side effects are currently the fourth leading cause of death in the U.S.
31 internautes sur 31 ont trouvé ce commentaire utile 
5.0 étoiles sur 5 half of us need mega dose niacin (vitamin B3) 9 janvier 2014
Par D&D - Publié sur Amazon.com
Basic pellagra, niacin (vitamin B3) deficiency, was eradicated last century but it turns out we are suffering advanced pellagra in our millions, perhaps billions. Huge doses of niacin cures the more dreadful symptoms of advanced pellagra: dermatitis, psychosis, dementia, diarrhea and heart enlargement.

Mega-doses also have been shown to cure TB, arthritis, addictions, various skin diseases, cardiovascular disease, coronary disease, stroke disorders and kidney disease. Dementia (schizophrenia/bipolar/psychosis/a large variety of psychiatric syndromes) is helped - even severely mentally ill people get well on [mega-dose] vitamin B3. Also Meniere's syndrome and high-tone deafness are helped as well as a whole range of other problems, including Alzheimer's and PTSD.

High-dose niacin also increases gastric acidity, which is a good thing. Even though many of us take antacids, the older/iller we get, the less stomach acid we can make actually: the symptoms of low or high stomach acid are the same.

For the anxious, or hyperactive types and those with lack of focus, high-dose niacin causes a pleasant calmative effect and is an excellent antidepressant. It is a systemic therapeutic agent. It measurably improves joint mobility, muscle strength, decreases fatigability and increases maximal muscle working capacity.

There's a fascinating part that explains how schizophrenia and pellagra are clinically the same - they differ only in that pellagra needs small doses in most cases and schizophrenia needs large doses in most cases. Schizophrenia patients, before they become sick and after they recover, have many physical and psychological advantages over the population lacking their schizo genes, including being less likely to get cancer. Schizophrenics are apparently more creative and enterprising; they tend to see relationships in the world that the rest of us do not see (like taking LSD); and have an evolutionary advantage but need lots of B3. TB apparently increases susceptibility towards schizophrenia.

It's worth knowing that excess niacin (B3) is metabolized by methylation and thus uses up methyl groups. So, if you don't do well with high-dose niacin supplements, you may be an under-methylator (45% of us are), meaning deficient, and would benefit from supplements containing taurine, GABA [both precursors to methyl activity in the brain], folate/B9 (NOT folic acid, a synthetic B9 that can cause cancer) B12, B6, DMG, TMG (and SAMe). If you are an over-methylator (that's 15% of us), meaning you have extra, then B3 is good because it uses them up.

The book has some great phrases and paragraphs:

Niacin is without a doubt a powerful detoxifying agent. The body seems to need proportionally more niacin than the other B vitamins. Niacin is not a true vitamin in the strictest sense of the term since it can be produced in the body but it's an inefficient process.

Nutritional therapy is inexpensive, effective and, most important, safe. There is not even one death per year from vitamins. (By contrast, death by doctor is fast overtaking the current leading causes of death.)

When dealing with vitamins, taking more than the optimum requirement is not harmful unless enormous doses are taken. This is in striking contrast with pharmaceutical drugs, where taking too much is much more harmful than taking too little. Just the opposite is true with vitamins. Taking too little is more harmful than taking too much - again within reason.

The key to niacin therapy are quantity, frequency and duration. You need to take enough, take it frequently and take it long enough to see benefit (in some cases, several years). The quantity of a nutritional supplement required to cure an illness indicates the patient's degree of deficiency. It is therefore not a megadose of the vitamin but rather a megadeficiency of the nutrient.

The number-one side effect of vitamins is failure to take enough of them. With vitamin therapy speed of recovery is proportional to the dosage given. Just as there is a certain, large amount of fuel needed to launch an aircraft or a spacecraft, there is a certain, large amount of nutrients needed to cure a sick body.

With vitamin therapy, speed of recovery is in proportion to dosage used. Much less is needed for prevention. Genetic disease in babies has been cured by giving them vitamins. IQ is proportional to nutrient dosage.

The difference between deficiency and dependency is explained by an example: pellagra (which needs small doses) is a deficiency and schizophrenia (and other problems needing high doses) is a dependency.

The book covers amounts to take, the famous niacin flush and what it means, also antidotes, the different types of B3, overdose symptoms (nausea, then vomiting) and side effects (most are positive), toxicity (has never been reached, not even at 40,000mg daily), various myths, the cluelessness of many doctors, and the fact that there has never been a single death due to niacin.

Side effects that may occur with really high doses of niacin are partly or largely offset by taking large doses of vitamin C (as ascorbic acid) - at least as much C as niacin. More C works even better. Side effects of niacin are specific to the patient's prior conditions and to the dose. (Further, vitamin C is an effective and nearly all-purpose antitoxin, antibiotic and antiviral.)

In "Hospitals and Health" it is explained that doctors frequently give patients 2,000-5,000mg of niacin to lower serum cholesterol and that Dr Hoffer estimated that over about 200,000mg per day could be fatal (this is a huge level that no one has been known to take). People with a history of heavy alcohol use, liver disorders, diabetes or pregnancy need to have a knowledgeable physician monitor their use of high-dose niacin. Negative side effects of high-dose niacin may be minimized with high-dose vitamin C, as they may be a result of low antioxidant status. Positive side effects include better general health, improved healing and prolonged higher quality of life.

Amazon reader Rachael Jean wrote a great comment to one of my other reviews which is relevant to this one. Partly paraphrasing her, she explained: I strongly believe that niacin deficiency, which shares its symptoms with thiamine deficiency, is a direct RESULT of thiamine deficiency. Both are triggered by food poisoning and too much sugar in the diet and both are helped by removing carbohydrates and eating plenty of red meats, especially organ meats (liver, kidneys, heart, brains etc).

Bacterial overgrowth in the small intestine and urinary tract system cause a thiamine [and niacin] deficiency. The bacteria produce an enzyme called thiaminase which depletes thiamine from the body. Part of the reason for overgrowth is low stomach acid. Thiamine deficiency also appears to be a cause for low stomach acid (which I found out myself through random searches on the internet not through any book) so things get worse.

The problem is, you can remedy low stomach acid with thiamine HCL but it won't completely resolve until the infection of the small intestine is completely cleared up, which is not easy [D&D note: partly because an adrenal deficiency - which is the most common problem today - can create weak sphincters. A weak sphincter between the small and large intestines allows fecal matter from the large intestine to ooze back into the small intestine, continually infecting it. "Stop The Thyroid Madness" has the 2 best chapters on adrenal deficiency I've come across, because half of those with low thyroid also have adrenal issues.]

Then, even if you stop the infection using antibiotics [D&D note: long term or frequent antibiotic use is dangerous, the herbal tincture wormwood (twice daily) kills all intestine bacteria - good and bad - as well as aiding digestion and bile, so also take a good probiotic half an hour after the wormwood], the infection will return if normal GI function is not restored. I am suggesting that thiamine would do this.... I strongly believe that niacin deficiency which shares its symptoms with thiamine deficiency is a direct RESULT of thiamine deficiency. Both are triggered by food poisoning and too much sugar in the diet and are both reversed by removing carbohydrates and eating plenty of red meats, especially organ meats (liver, kidneys, heart, brains etc.)

Thiamine also regulates and metabolizes blood glucose and is what primarily causes hydrochloric acid in the stomach, regulating digestive juices of the stomach acid and bile from the liver and rhythms of the small intestines. Consuming more than 3 tsp of sugar a day will deplete your body of thiamine in less than 2 weeks because thiamine is stored in the body in limited quantities, mainly in the brain, heart, liver and kidneys. ...

I am using these supplements to (successfully) treat my husband's heart failure: 500 mg thiamine HCL 2x a day, 500 mg SCHIFF brand inositol hexiniacinate 2x a day (other brands caused liver inflammation), 12.5 mg of iodoral (iodine) 2x a day, B6 100 mg 2x a day, and 400 mg of magnesium oxide 1x a day. [D&D note: the niacin book advises taking at least as much vitamin C as the niacin/thiamine supplements]

Later note: see my review on "Supplements Exposed" by Clement about the dangers of most vitamins, which are synthetic. "The Calcium Lie II" an intriguing book plausibly claiming to explain the root cause of most illnesses, also warns against synthetic supplements and suggests stablized rice bran as a good source of natural niacin. I have identified that natural vitamins are available from Premier Research and Innate Response and Standard Process.
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