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The Alzheimer Conundrum - Entanglements of Dementia and Aging (Anglais) Relié – 12 novembre 2013


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Because of rapidly aging populations, the number of people worldwide experiencing dementia is increasing and the projections are grim. Despite hundreds of millions of dollars invested in medical research, no effective treatment has been discovered for Alzheimer's disease, the most common form of dementia. The Alzheimer Conundrum exposes the predicaments embedded in current efforts to slow down or halt Alzheimer's disease through early detection of presymptomatic biological changes in healthy individuals. Based on a careful study of the history of Alzheimer's disease and extensive in-depth interviews with clinicians, scientists, epidemiologists, geneticists, and others, Margaret Lock highlights the limitations and the dissent implicated in this approach. She stresses that one major difficulty is the well-documented absence of behavioral signs of Alzheimer's disease in a significant proportion of elderly individuals, even when Alzheimer neuropathology is present in their brains. This incongruity makes it difficult to distinguish between what counts as normal versus pathological and, further, makes it evident that social and biological processes contribute inseparably to aging.Lock argues that basic research must continue, but it should be complemented by a realistic public health approach available everywhere that will be more effective and more humane than one focused almost exclusively on an increasingly frenzied search for a cure.


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8 internautes sur 8 ont trouvé ce commentaire utile 
Great overview of AD research and the various political camps 8 décembre 2013
Par Henry - Publié sur Amazon.com
Format: Format Kindle Achat vérifié
This book takes work to read as it uses many medical terms that are not familiar to the general consumer. I have a dictionary APP installed on my iPad that displays the definition as one goes simply by touching the word and it found these words so I was able to stay up with the narrative. If one is looking for something to give one hope that a solution to AD is in the immediate future than this book will be a major disappointment. The author is surveying the research landscape and its controversial nature including the political gamesmanship being played by individuals and organizations especially those committed to the arguably failed notion of BAP as the single interior brain mechanism causing AD.

Bottom line - i would think this would be valuable reading for researcher in AD or medical professional. If you are a consumer and your interest is in AD as a disease and how it might someday be controlled or eliminated like one might be interested in cancer or any other ubiquitous disease thn this is an interesting read. It can serve as a guide to how one might direct contributions, organizations to support and the extent of political involvement in the funding. AS note earlier it is not for the caregiver or sufferer looking for information that can be acted upon now.
The Alzheimer Conundrum presents a challenge to bio-medical scientific thinking 1 août 2014
Par Susan mass ad - Publié sur Amazon.com
Format: Format Kindle Achat vérifié
Lock brings enormous scholarship to this fascinating book on Alzheimer's Disease. It is the story of medical science and contemporary research and raises interesting philosophical and methodological questions about our current understandings of research, knowing, causality and truth in biomedical sciences. It was my first encounter with someone who gave clear expression to what is an emerging post-modern understanding of biology and biological processes.
0 internautes sur 2 ont trouvé ce commentaire utile 
Where's the PDF file with Illustrations? 20 décembre 2013
Par Lawrence M G Enomoto - Publié sur Amazon.com
The narrator mentioned several times that a PDF with illustrations could be downloaded from where the audio edition was sold. Having the illustrations cited would have made the audio edition more meaningful. Is it too late to get that PDF file with illustrations cited?
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