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The Epigenetics Revolution: How Modern Biology is Rewriting our Understanding of Genetics, Disease and Inheritance
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The Epigenetics Revolution: How Modern Biology is Rewriting our Understanding of Genetics, Disease and Inheritance [Format Kindle]

Nessa Carey
5.0 étoiles sur 5  Voir tous les commentaires (1 commentaire client)

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At the beginning of this century enormous progress had been made in genetics. The Human Genome Project finished sequencing human DNA. It seemed it was only a matter of time until we had all the answers to the secrets of life on this planet. The cutting-edge of biology, however, is telling us that we still don't even know all of the questions. How is it that, despite each cell in your body carrying exactly the same DNA, you don't have teeth growing out of your eyeballs or toenails on your liver? How is it that identical twins share exactly the same DNA and yet can exhibit dramatic differences in the way that they live and grow? It turns out that cells read the genetic code in DNA more like a script to be interpreted than a mould that replicates the same result each time. This is epigenetics and it's the fastest-moving field in biology today. The Epigenetics Revolution traces the thrilling path this discipline has taken over the last twenty years. Biologist Nessa Carey deftly explains such diverse phenomena as how queen bees and ants control their colonies, why tortoiseshell cats are always female, why some plants need a period of cold before they can flower, why we age, develop disease and become addicted to drugs, and much more. Most excitingly, Carey reveals the amazing possibilities for humankind that epigenetics offers for us all - and in the surprisingly near future.

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2 internautes sur 2 ont trouvé ce commentaire utile 
5.0 étoiles sur 5 excellent 11 mars 2013
Format:Broché|Achat vérifié
Une vraie révolution comme il y en a tant actuellement.
Quelle chance a l'humanité de saisir la vérité et grimper vertigineusement.
Le livre est en parfait état et correspond à ce que je souhaitais.
La livraison, les délais, tout a été impeccable
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Commentaires client les plus utiles sur (beta) 4.6 étoiles sur 5  76 commentaires
53 internautes sur 54 ont trouvé ce commentaire utile 
5.0 étoiles sur 5 Great science book! 4 juin 2012
Par Gavin Scott - Publié sur
This is one of those books that introduces an entirely new and fascinating topic. A similar work would be Chaos: Making a New Science which introduced the concepts of chaotic dynamical systems at a time when even many practitioners of the sciences would not have heard of it.

Similarly, this book introduces the discoveries in epigenetics (epi- meaning "on", or a layer on top of classical genetics) and pretty much all of this will be new information unless you have been actively working in the field of cell biology over the past few years.

The book talks about the paradigm shift that is occurring as cell biologists are realizing that this epigenetic information is as complex and important to the correct function of life as the underlying DNA genome, and even allows for Lamarckian inheritance in certain cases where an offspring's own epigenetic information and phenotype can be influenced by that of the parents, meaning that some environmental effects in a parent's life can directly influence future generations.

Also much of the non-protein-coding genome that for many years was considered to be unimportant "junk" is now turning out to be very important as it can be transcribed into functional RNA molecules that perform important functions. The book contains a simple graphic showing that the ratio of the non-protein-coding DNA to that of traditional protein coding genes increases in direct proportion with the complexity of the organism. The fundamental genes and proteins between say a chimpanzee and a human are virtually identical and it now begins to look as though it's that "junk" DNA that makes all the difference.

This is a fascinating look at recent developments in the ever-accelerating biological revolution and I highly recommend it to everyone who yearns to understand how life works.

30 internautes sur 31 ont trouvé ce commentaire utile 
5.0 étoiles sur 5 Could hardly be more fascinating! 2 janvier 2012
Par tiggrie AKA Sarah - Publié sur
Format:Format Kindle
Word of warning - I may gush! I'm no biologist, but Nessa Carey manages to make epigenetics clear and incredibly interesting to me. This is not an easy read, in that it requires one to think and occasionally to do a little mental gymnastics to get one's head around the concepts she introduces, but nevertheless it's the kind of book that can be gulped down in large servings because Carey is skilled at explaining these high-falutin' concepts so well.

The topics range from inherited traits to cloning and back again, and I found even the descriptions of how certain experiments were undertaken were such that they read incredibly well. This is a book that could havebeen dry as dust, but it's not.

I think probably one where the time taken to read the sample is well spent - I'm sure some people just won't find this that interesting - but if you are at all interested in science, biology, DNA, and the mystery of how things are and aren't passed on, then this is a must read. Absorbing, educational, and downright fascinating. Brilliant.
19 internautes sur 20 ont trouvé ce commentaire utile 
5.0 étoiles sur 5 Superb Reading 16 juin 2012
Par Deborah DePreta - Publié sur
Format:Relié|Achat vérifié
What a refreshingly erudite and informative book! It was in-depth, at times jam packed with information, particularly for a person with no biology background, but the author went to great length to explain in a very understandable manner some of the complexity of epigenetics, genetics and the current state of our knowledge about these subjects. I highly recommend this book for the interested reader.
17 internautes sur 19 ont trouvé ce commentaire utile 
5.0 étoiles sur 5 Simple, but not simplistic 18 décembre 2012
Par Arnie Berg - Publié sur
I am writing as a person with a graduate degree in Bioinformatics with a special interest in epigenetics, and I can confidently say that this is one of the clearest introductory presentations of epigenetics that I have encountered. The book is written at the undergraduate level, but it is not simplistic. It hits all the high points of epigenetics and pulls together the latest in research into this fascinating area of science. Anyone with a rudimentary background in genetics should have no trouble absorbing the concepts articulated in this book.
15 internautes sur 17 ont trouvé ce commentaire utile 
4.0 étoiles sur 5 Fasinating 31 octobre 2012
Par William Tell - Publié sur
Some readers may find this review of a critically important emerging field of science over detailed. It's not written for lightweights or readers of US Today. But it's well worth the time and effort and yields a host of fascinating facts, observations and predictions. Its subject matter is the very essence of life, your life and those around you. It is, as the title infers, revolutionary. The understanding of how we influence our genes (and of course are influenced by them) is changing rapidly and the author clearly has a magnificent grasp of the facts, the science and researchers on the cutting edge. A number of her predictions have already come true (including the latest Nobel Prize winners) and her speculations about the future alone are worth the price. I rate the book 4 (rather than 5) as it dwells excessively on details of biochemistry that, for the layman, might seem unnecessary to understand the bigger picture. But that aside it was absolutely fascinating and thought provoking.

This book may be obsolete in 2 years so pick it up now and be amazed by what has been learned and humbled by how much has yet to understood.
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