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In Search of Memory - The Emergence of a New Science of Mind (Anglais) Broché – 24 avril 2007

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Description du produit

Revue de presse

"A scrupulously detailed yet magnificently panoramic autobiography." --The New York Times Book Review

"[A] scintillating mix of memoir, history of science, and fundamental biology without peer. It shows compellingly what first-rate science is and how it is created." --E.O. Wilson

"Few can interlace their autobiography with the evolution of a scientific paradigm. Even fewer can weave such a story seamlessly. Eric Kandel is one of these." --Nature

Présentation de l'éditeur

"Beyond autobiography, the book is also an accessible introduction to contemporary neuroscience, the study of how the brain produces thought and action. Included are brilliant vignettes on the history of neuroscience." Times Literary Supplement

Memory binds our mental life together. We are who we are in large part because of what we learn and remember. But how does the brain create memories? Nobel Prize winner Eric R. Kandel intertwines the intellectual history of the powerful new science of the mind-a combination of cognitive psychology, neuroscience, and molecular biology-with his own personal quest to understand memory. A deft mixture of memoir and history, modern biology and behavior, In Search of Memory brings readers from Kandel's childhood in Nazi-occupied Vienna to the forefront of one of the great scientific endeavors of the twentieth century: the search for the biological basis of memory.

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Format: Broché Achat vérifié
Erik Kandel won the Nobel Prize for his path-breaking work on the cerebral mechanisms that produce memory. In this popular science book, he offers an illuminating description of his own research spanning several decades in relation to the general advancement of the topic. He knows how to use simple pictures to convey the key points and the reader learns painlessly quite a lot about his own brain and how his own mind functions. Moreover, Kandel blends his own memories with his narrative, from his beloved Vienna that his family had to leave when the Nazis took over, to New York, where he spent the rest of his life.
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Format: Broché
Bonjour,
Ce livre était un cadeau pour célébrer les 48 ans de mon fils qui vient de le recevoir avec beaucoup de plaisir et de surprise !
Je ne l'ai évidemment pas vu, mais tout doit être bien comme d'habitude.
Merci
Cordialement
Simone Maubouché
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Commentaires client les plus utiles sur Amazon.com (beta) (Peut contenir des commentaires issus du programme Early Reviewer Rewards)

Amazon.com: 4.5 étoiles sur 5 140 commentaires
4 internautes sur 4 ont trouvé ce commentaire utile 
5.0 étoiles sur 5 10 stars for a must read book 14 décembre 2016
Par Camp Runamok - Publié sur Amazon.com
Format: Format Kindle Achat vérifié
This was for me one of those magical books - the kind I wish I had not yet read, so I could read it again for first time.​ ​In Search of Memory​ is the story of Eric Kandel and the search for the biology of memory, but it's also a definitive history of the science of neurology and the brain, as well as a book about what it means to be a scientist determined to explore the unknown on the path not only less traveled, but more often than not, a path not yet imagined.

As a Jew who was chased out of Vienna as a child, Kandel also details the Austrian embrace of the Nazis, their purge of the Jews, and the inability of post war Austria to acknowledge its dominant role in the holocaust (following annexation, Austrians made up about 8 percent of the population of the greater reich, yet they held most of the key positions and accounted for more than 30 percent of the officials working to eliminate the Jews).​

Unless you are already conversant in the biology of neurology, parts of this book will be a​t times a​ very slow read, but one well worth the investment​. Besides the science, you will also get a comprehensive look and appreciation for virtually all the other key players in neuroscience​. The writing is extraordinarily. Kandel does a masterful job of explaining neuroscience in a way that anyone can understand. The biographical and historical elements are equally engrossing. If I could, I would give this book 10 stars​ on Amazon​.
1 internautes sur 1 ont trouvé ce commentaire utile 
5.0 étoiles sur 5 A Wonderful Book 15 février 2014
Par Richard B. Schwartz - Publié sur Amazon.com
Format: Broché Achat vérifié
This is a wonderful book, but it is actually two books in one. It is the autobiography of a Nobel laureate and, along the way, a history of modern studies of the brain and memory. Kandel and his family escape Nazi Vienna and come to New York. He studies medicine, intending to be a psychoanalyst, but then discovers the new science of the mind—molecular biology, neuroscience and cognitive psychology. He makes brilliant strides through the in-depth study of a particular creature, Aplysia, a large sea snail. As his new life unfolds in the United States (principally at Columbia), so does the study of the brain and the two become inextricably linked.

Initially studying the humanities, Kandel is, like most wise people, broadly educated. One of the ongoing themes of In Search of Memory is the manner in which dry neuroscience anticipates and reinforces wet neuroscience. Humor theory in antiquity and the renaissance . . . the empiricism of the British philosophers . . . the Kantian ‘categories’ . . . the hypothetical, abstract constructs of Freud . . . all find some degree of confirmation in the discoveries and tentative conclusions of laboratory scientists in the 20th and 21st centuries.

The writing is very lucid and even when the story becomes increasingly complex, with the discovery of additional neurotransmitters and electro/chemical processes, non-scientific readers are able to follow the exposition and line of argument.

The book also looks to the future, with the daunting challenges of understanding consciousness and the teasing possibilities of integrating neuroscience with such fields as sociology.

Kandel is likable, engaging, and courageous, as when he presses contemporary Austrians to come to terms with their complicity in National Socialism and the holocaust. He is a cultured man, complementing his knowledge of science with his love of the arts and music. He is also a generous man, sharing the limelight with collaborators and colleagues. In some passages his autobiography constitutes an examination of the sociology, economy and ethos of those who do serious science.

If you are interested in following the life of a very interesting man as well as following the course of modern neuroscience, this would be an ideal place to start. It is also rich in its illustrations and it includes a 20+ page glossary which is very, very helpful.

Highly recommended.
2 internautes sur 2 ont trouvé ce commentaire utile 
5.0 étoiles sur 5 A Good Read!! 16 juillet 2016
Par F. Winquist - Publié sur Amazon.com
Format: Broché Achat vérifié
This book is ten years old so it obviously cannot reflect the current state of neuroscience developments, that said however I found the book to be very informative and interesting even after having read his "Principles of Neural Science" four years ago. He covers very comprehensively all the historical milestones and major contributors to neurobiology.
1 internautes sur 1 ont trouvé ce commentaire utile 
5.0 étoiles sur 5 Immensely readable discussion of memory following the authors personal history 7 mai 2012
Par A. Menon - Publié sur Amazon.com
Format: Broché Achat vérifié
I bought this book when it was first published but for some reason got distracted while reading it the first time and put it down. Luckily i recently decided to pick it up again- the book is fantastic. In search of Memory is a mixture of autobiography and science. The author constructs the book around his own history and his own motivation both for study of memory. The book is split into 6 sections with the first and last focused on personal history and the middle four focused on the author's work. All is engaging and readible and highly recommended, I will give a brief overview of the sections.

In the first section the author describes his childhood in Vienna with the Nazi invasion and the persecution he and his family faced- he describes the hardships faced and the journey taken to go to the US. In this section the stage is set to pose the questions about how memory works. In particular, how memories can be so clear so far from the date of experience in certain situations and where this permanence is formed and stored is pondered. Though few can empathize with the author's experience all can sympathize with the questions about the basis for memory.

The author works chronologically and goes through his early history working with biological and neurological questions. Practical neuroscience and biological problems are considered and so is the authors journey that took him to study the right system to consider memory. The author throughout the book makes it a point to argue that finding the right simple system to analyze that can give broader implication is at the heart of putting oneself in a position to make progress. The author settled on the sea slug Aplysia. So too are discussed were the experience of the author in first monitoring of action potentials in the squid nervous system. A creature with nerve cells relatively easy to monitor.

The author moves onto trying to monitor change in the nervous system after becoming comfortable with the Aplysia's biology. Reflex behaviour is studied and the monitoring of nerve cells is examined when presented with various stimulus. The chemical reactions that take place within the cell and the neurotransmitters that are associated are discussed and in particular the mechanics of short term memory adaptation and implication to behaviour are discussed in detail through the results of experiments done. The author continues on to pose questions about long term memory and how short term and long term though different, must be associated somehow. The mechanics for this are not understood but insight is provided by the author and the subject matter is fascinating.

The author continues in complexity and starts to discuss things like perception and spacial awareness. Spacial awareness is definitely an arena to explore how memory works given our spacial awareness and that of most creatures is a function of nature in initial architecture as well as environment which determines how the memory implicit in a mental map is formed. This process is being explored in current science and the idea of paying attention is also discussed.

The author moves on to modern biomedical progress and how understanding memory processes in mice has provided a means to develop insight and treatment into memory related diseases. The author discusses how biology is an incredibly important part for the future of psychiatry. In particular the rigour of science should be applied to psychiatry to get an objective measure of results. Interaction of people is shown to be very important for developement and treatment is not chemistry when it comes to social disorders and mental disorders like depression and schizophrenia. The author also walks through some of his thoughts on the collaboration of the private and public sector in the field of pharmaceuticals.

The author concludes with his receiving of the Nobel prize. It is a return to the autobiographical aspect of the book and the author describes how he revisited Vienna and some of the discourse engaged in while there. It is a reasonable end to an otherwise fascinating and informative book.
5.0 étoiles sur 5 Partial feedback for a volume half read 11 octobre 2012
Par Dr. Doug's reflections - Publié sur Amazon.com
Format: Broché Achat vérifié
I had never heard of Kandel, until this autobiography. It is so many things: personal, comprehensive, with novelist flair for drama, particularly valuable as it sets his inquiring mind/research in the context of historical neuroscientific enterprise -- from the likes of Cajal and Helmholtz of the 19th century to so many noteworthy pioneers, alla Joseph Le Doux, in the 20th. Who could ever have imagined that the lowly sea creature, the Aplysa -- I hope that I have spelled it correctly -- would reveal so much about the nature of learning and memory, relevant to higher order creatures, particularly we humans. Kandel is generous in his citations of the 'shoulders of others' and their explorations, interweaving their discoveries with his own. Carefully, he leads the reader from broad view (i.e. behavior)inexorably to the microscopic (e.g. experience creating dendrite formation), and eventually, of course, to the molecular. (Reminding me of Keysey's opening pages in Sometimes a Great Notion.) Especially valuable is the way he dovetails his own research with succinct summaries of others in theirs that leads to his own hypotheses and consequent research, exploring, heretofore, that which could not even be imagined. Then, too, call it awesome fortuitousness that we even have an Eric Kandel, so close was the youthful fellow and his Jewish Vienna family to the Nazi maw and genocidal oblivion. Finally,as an aside, I found fascinating the role of Karl Lashley, whose very fame served to impede pioneering brain science exploration.

As a non neuroscientific clinician, nonetheless fascinated by brain research for the last couple of years, I find this tome invaluable. Don't waste your time, if you are in a rush. The extensive glossary is a most helpful tool for the otherwise unitiated, as myself. The drawings provided are also most helpful. Lastly, I found myself in tears, several times, moved by his accounts of relations with intimates both familial and collegial -- surely surprising for such erudite reportage.
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